产品货号：
GS4543
中文名称：
重组人sTRAILR2/TNFRSF10B
英文名称：
Recombinant Human soluble Tumor Necrosis Factor-Related Apoptosis-inducing Ligand Receptor-2
产品规格：
10μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 14.8kDa,a single non-glycosylated polypeptide chain containing 132 amino acids.
储存条件：冷冻（-20℃）
概述
Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2(TRAIL-R2)is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)-induced cell-death signaling.The death ligand TRAIL bears high potential as a new anticancer agent,as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人sTRAILR2/TNFRSF10B，sTRAILR2/TNFRSF10B, Human
储存条件：冷冻（-20℃）
概述
Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2(TRAIL-R2)is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)-induced cell-death signaling.The death ligand TRAIL bears high potential as a new anticancer agent,as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.rHusTRAIL-R2 reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC.In this assay,endogenous TRAIL is induced during a 24hourexposure to LPS(10ng/mL)but in the presence of rHusTRAIL-R2,TRAIL-induced TNF is suppressed. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rHusTRAIL-R2 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | ESALITQQDL APQQRAAPQQ KRSSPSEGLC PPGHHISEDG RDCISCKYGQ DYSTHWNDLL FCLRCTRCDS GEVELSPCTT TRNTVCQCEE GTFREEDSPE MCRKCRTGCP RGMVKVGDCT PWSDIECVHK ES |
相关搜索：重组人sTRAILR2/TNFRSF10B，sTRAILR2/TNFRSF10B, Human